Researchers are now using the ISS U.S. National Laboratory for innovative stem-cell, 3D-tissue-modeling, and tissue-chip research that cannot be done on Earth. Stem cells are one of the cornerstones for regenerative medicine applications, and studies conducted on the ISS with stem cells are aimed at advancing therapeutics on Earth. Each day, an average of 22 people die waiting to receive life-saving organs. Advancing stem research and 3D tissue models are the first steps in understanding how to grow tissues, and eventually whole organs, for transplantation to enhance patient care on this planet.